I am planning on doing a project on the Winner's Curse. The Winner's Curse applies to genetics in the sense that most genetics effects detected are due to luck. Think of the mean as being 0 and a winner gets a positive result just by chance. In the future that same person may get a less positive or even a negative result. In other words most genetic effects detected are not real but due to random effects. Repeating the study will show the genetic effects to be weaker than was previously thought.
I want to show how using replicated samples one can correct for effect sizes using a winner's curse. I may eventually try to develop a statistic to correct for the winner's curse.
Next week I will read the article by Jonathen Pritchard and Sebastian Zollner called "Overcoming the Winner's Curse: Estimating Penetrance Parameters from Case-Control Data"
I deserve an A for doing what I was supposed to this week.

Week 5: Read the paper.
For week 5 I fully read the paper, so I deserve an A.

Week 6: Begin to write a program to access and replicate HapMap data
For week 6 I wrote the program and did the easy part of the Winner's Curse Project, so I deserve an A.

Week 7: Continue writing program.
I deserve an A+ for finishing the project.

Week 8: Begin work on PowerPoint presentation.
Week 9: Finish work on PowerPoint presentation.
I deserve an A for correcting a flaw with my statistic.

I am now going to write a paper telling what I did.
I uploaded the paper telling what I did as well as the slides. Therefore, I deserve an A.

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